Searchable abstracts of presentations at key conferences in endocrinology

ea0020p20 | Adrenal | ECE2009

Chemokine receptor expression in the adrenal cortex and in adrenocortical tumours

Lang Katharina , Sturmer Andrea , Adam Patrick , Fassnacht Martin , Quinkler Marcus , Morcos Michael , Allolio Bruno , Hahner Stefanie

Introduction: Chemokines and their receptors (CR) have been demonstrated to be involved in tumour growth and site specific metastasis. Furthermore, several cytokines have been described to modulate adrenocortical function. Therefore, we have investigated the expression pattern and functional activity of chemokine receptors and of corresponding chemokines in adrenocortical tissue.Methods: Chemokine and CR expression was assessed by RT-PCR in normal adrena...